Jimmy Kimmel made a humorous return to his late-night show, sharply criticizing Donald Trump for selecting Ohio Senator JD Vance as his running mate, calling it a 'huge mistake.' Kimmel mocked Vance's appearance and his controversial comments about women, remarking that Vance looked like 'someone asked AI to make the Two and a Half Men one person.' He contrasted Vance unfavorably with Kamala Harris's pick, Minnesota Governor Tim Walz, whom he praised for his personable nature. Kimmel further joked about the dubious decision-making process behind Vance's selection, suggesting it might have been influenced by Trump Jr. Kimmel also lampooned Trump's claims regarding Harris's treatment of former Vice President Mike Pence, quipping that Pence might even vote for Harris. This monologue reflects the evolving political landscape as the 2024 election approaches.