The U.S. Supreme Court's recent decision to overturn the Chevron deference ruling is expected to lead to significant changes across multiple sectors. By limiting federal agencies' ability to interpret ambiguous laws, the ruling shifts power to the courts, potentially complicating regulatory enforcement concerning the environment, public health, and healthcare. This could make it harder for agencies like the EPA and FDA to set rules, possibly leading to prolonged litigations and inconsistent regulations nationwide. The decision also raises uncertainties in fields such as tribal sovereignty, immigration, and water protection, with experts warning of potential delays in addressing critical issues like PFAS contamination. While some see potential benefits, such as more opportunities to appeal immigration cases, many predict increased instability and legal challenges across various regulatory frameworks.