Colorado Governor Jared Polis, a Democrat, has sparked controversy by expressing support for President-elect Donald Trump's appointment of Robert F. Kennedy Jr. as Health and Human Services Secretary. Despite Kennedy's anti-vaccine stance and history of spreading public health conspiracies, Polis highlighted his potential to challenge big pharma and corporate agriculture. Polis's endorsement, articulated via the social media platform X, drew immediate backlash from both Democrats and the public, given his previous criticism of Kennedy's vaccine views. He later clarified that while he supports Kennedy's opposition to vaccine mandates and hopes for a shake-up in health institutions, science should remain central to health policy. Trump's appointment of Kennedy is seen by some as a significant shift in public health policy, with a focus on reducing pharmaceutical influence and promoting personal vaccine choice. The nomination has received mixed reactions, with some viewing it as an opportunity for reform and others as a threat to public health infrastructure.