Grey's Anatomy is set to introduce a new character, James, played by Michael Thomas Grant, in its upcoming 21st season premiering on September 26 at 10 PM ET. James is described as an openly gay Episcopal chaplain, who is warm and great with younger patients, while also navigating personal challenges related to love and faith. This addition comes as previous LGBTQ+ characters, including Jake Borelli's Levi Schmitt, are exiting the show, prompting a need for new representation. The upcoming season will also see notable changes such as the return of Jason George's character, Ben Warren, and a larger presence of Ellen Pompeo's Meredith Grey. The series continues to evolve with these developments and shifts in the cast dynamics. Fans can expect a fresh perspective as the series moves forward with its evolving storylines.