Texans RB Joe Mixon Ruled Out Week 1 With Foot Injury

Houston Texans star running back Joe Mixon is expected to miss the majority, if not the entirety, of the 2025 preseason due to a persistent foot and ankle injury that has lingered since last season and was aggravated during offseason training. Mixon, who started training camp on the non-football injury list, is undergoing gradual rehabilitation with the goal of being ready for the Texans' season opener against the Los Angeles Rams, but his availability for Week 1 remains uncertain. Despite the injury setback, Mixon's medical outlook is cautiously optimistic, as he has made significant progress in recovery, though the Texans will rely heavily on Nick Chubb and other backs like Dare Ogunbowale and Woody Marks to fill the void during his absence. Mixon's injury comes at a critical time as the Texans are installing a revamped offensive system under new coordinator Nick Caley, making his absence during training camp and preseason snaps a potential challenge for team chemistry. The Texans had hoped Mixon's proven rushing ability—demonstrated by his 1,016 yards and 11 touchdowns in 14 games last season—would elevate their offense, but they have prepared for contingencies by strengthening their running back depth. While Mixon's recovery timeline is still uncertain, the Texans remain focused on his eventual return and are adjusting their game plans accordingly.