Several key college football matchups are scheduled for Week 10, including Arkansas vs. Ole Miss and Ohio State vs. Penn State, both early on November 2, broadcast on major networks like ABC and FOX. Auburn will host Vanderbilt at a similar time, while Oklahoma State aims to secure their first Big 12 win in a primetime game against Arizona State on FS1. Iowa State looks to extend their unbeaten streak against Texas Tech, and Memphis will face UTSA, both with afternoon kickoffs on ESPN networks. Additionally, Alabama hosts Missouri in a critical SEC matchup, seeking to avoid a third conference loss at homecoming, with the game airing on ABC. These games highlight pivotal matchups across college football, reflecting teams' efforts to improve standings and pursue postseason opportunities.