Indiana Football Opens As 21.5-Point Favorite At Maryland; Illinois, Minnesota Also Favored

This weekend's college football betting landscape features several notable matchups with significant point spreads and over/under totals. Indiana is heavily favored, with a 21.5-point spread over Maryland, reflecting Indiana's undefeated 8-0 record and strong recent performances, including a dominant win against UCLA. Minnesota is a 4.5-point favorite against struggling Michigan State, which is winless in Big Ten play and has one of the worst defenses nationally. Illinois enters as a sizable favorite over Rutgers, with lines ranging from 11.5 to 12.5 points, despite defensive challenges that have allowed nearly 40 points per game in Big Ten play. Rutgers, buoyed by a recent upset win over Purdue, aims to keep bowl hopes alive but faces difficulties against Illinois' effective running game and aggressive defense. These matchups highlight the stakes for teams fighting for rankings, bowl eligibility, and momentum as the college football season progresses.