NDM-CRE 'Nightmare Bacteria' Infections Surge Nearly 70% Across US, CDC Warns

The Centers for Disease Control and Prevention (CDC) has reported a significant rise in infections caused by drug-resistant "nightmare bacteria," specifically NDM-CRE, which increased by over 460% between 2019 and 2023. These bacteria, known for their resistance to most antibiotics due to the NDM gene, pose a serious health threat as they can cause severe infections like pneumonia, bloodstream infections, and urinary tract infections that are difficult to treat and have a high mortality rate. Only two antibiotics are effective against these infections, but they are costly and require intravenous administration, complicating treatment. The surge is attributed in part to antibiotic misuse and gaps in infection control, with cases primarily occurring in healthcare settings but with concern over potential community spread. Experts warn that common infections, once easily treatable, could become chronic and more dangerous, emphasizing the need for rigorous hygiene and testing protocols. The rise in these bacteria underscores the urgent need for improved antibiotic stewardship and public health measures to prevent further spread.