Grey's Anatomy is set to return for its 21st season on September 26, 2024, making it ABC's longest-running medical drama. The new season will continue to explore ongoing character arcs, including Meredith Grey's research on Alzheimer's, Jo Wilson's pregnancy, and the fallout from a recent wrongful death incident involving intern Lucas Adams. Notably, this season marks the first without the crossover series Station 19, although familiar faces like Jason George will return in recurring roles. As fans reminisce about memorable storylines from the previous 20 seasons, the show’s creators and cast are praised for their commitment, which has led to nearly two decades of captivating drama and humor. The season will consist of 18 episodes, an increase from the 10 episodes of the previous season, which was affected by industry strikes. Streaming options for the new season will be available on Hulu following its premiere.