GLP-1 Drugs Linked to Alcohol, Heat Illness Effects

GLP-1 receptor agonists, initially developed for diabetes and obesity, are now being recognized for additional health effects, including a potential treatment role for alcohol use disorder. Recent studies report that regular drinkers using these medications experienced up to a 68% reduction in weekly alcohol intake. While these drugs do not increase psychiatric adverse events or worsen depression, they are linked to improved emotional well-being and quality of life for those with obesity or diabetes. Medical experts caution that GLP-1 drugs can elevate the risk of heat-related illnesses, particularly in patients with diabetes and heart disease, emphasizing the importance of hydration and heat vigilance. Evidence on dietary interventions for mood disorders remains limited, though calorie restriction and low-fat diets may modestly reduce depressive symptoms in at-risk adults. Overall, GLP-1 medications appear generally safe for mental health and may provide benefits beyond weight management, but certain physical risks require attention.