FSU Opens as Slight Underdog at Clemson in Key ACC Football Clash

The upcoming college football matchup between Clemson and Florida State (FSU) is highly anticipated but considered a toss-up by oddsmakers, with Clemson favored by a narrow margin of around 2.5 points. Both teams have struggled in the 2025 season, with Clemson holding a 3-5 record and FSU at 4-4, and each team showing inconsistency, such as Clemson's recent home losses and FSU breaking a losing streak with a dominant win over Wake Forest. The game, set to take place in Clemson's Death Valley stadium, carries little impact on ACC standings but significant pride for both programs. FSU has upgraded its roster through transfers and young talent, contributing to the close spread, while Clemson retains much of its previous year's team but has seen signs of wavering player morale. Historically, FSU leads the all-time series, but Clemson won the most recent meeting in 2024; this game marks the first consecutive yearly meeting since the late 1990s. Betting markets expect a potentially high-scoring game given both teams' offensive capabilities and defensive vulnerabilities.