New York Jets linebacker C.J. Mosley will miss the game against the New England Patriots due to a bruised big toe, which he sustained during last Sunday's win against the Tennessee Titans. Mosley, a key defensive player and the team's signal caller, did not practice all week and was listed as inactive for the game. Jamien Sherwood will step in to replace Mosley, with coach Robert Saleh expressing confidence in Sherwood's ability to handle the defensive calls. This marks only the second time in over three seasons that Mosley has been sidelined, the last occurrence also against the Patriots in 2021. The Jets are also dealing with other injuries, including the loss of edge rusher Jermaine Johnson to a torn Achilles tendon. Meanwhile, the Patriots will be without several key players, including starting left tackle Vederian Lowe and left guard Sidy Sow.