AMD Launches MI350, Previews MI400 With OpenAI Partnership

At its 2025 Advancing AI event, AMD unveiled the Instinct MI350 Series accelerators, which provide a fourfold increase in AI compute and a thirty-fivefold boost in inference performance compared to previous chips, with the MI355X variant delivering up to 40% more tokens-per-dollar than rivals. AMD previewed its next-generation MI400 chips, planned for release in 2026, and introduced the Helios rack-scale AI platform, enabling thousands of GPUs to operate as a unified compute engine for hyperscale AI tasks. OpenAI CEO Sam Altman confirmed that OpenAI will deploy both MI300X and MI400 series chips for its AI infrastructure, joining other major partners such as Meta, Microsoft, and Oracle. AMD emphasized its commitment to an open AI ecosystem by releasing ROCm 7, the latest version of its open-source AI software stack, and expanding the AMD Developer Cloud. The company positioned its hardware as offering superior price-performance and lower operational costs compared to Nvidia. Despite these announcements and strategic partnerships, AMD’s stock declined approximately 2% after the event.