Dewi Lake will captain Wales in the absence of Jac Morgan due to a hamstring injury, with several changes in the team lineup for the upcoming match against South Africa at Twickenham. Cardiff's Ellis Bevan will make his debut at scrum-half, while players like Liam Williams and Matthew Screech are set to start due to various player unavailability reasons. Coach Warren Gatland expressed excitement about the challenge ahead and the potential for development within the team over the next five weeks.