No. 13 LSU is set to face No. 23 USC Trojans at Allegiant Stadium in Las Vegas on Sunday, September 1, marking an opportunity for the Tigers to secure their first Week 1 victory since 2019. Head coach Brian Kelly has expressed optimism despite the departures of key players to the NFL, emphasizing the team's productive offseason and focus on winning a national championship. Wide receiver Chris Hilton is listed as questionable due to a bone bruise, with redshirt-freshman Kyle Parker likely to step in if Hilton is unable to play. Offensive lineman Miles Frazier is probable for the game. Key players like linebacker Greg Penn and running back Josh Williams are expected to lead the team. Kelly also highlighted the necessity of limiting USC's offensive big plays and the challenge posed by USC's Air Raid offense.