Jacksonville Jaguars tight end Evan Engram has been ruled out for the team's Week 2 game against the Cleveland Browns due to a hamstring injury sustained during pregame warmups. Engram, a key offensive player who recorded a career-high 114 catches last season, had only one catch for five yards in the previous game against the Miami Dolphins. His absence is a significant blow for quarterback Trevor Lawrence, especially against a strong Browns defense. Brenton Strange and Luke Farrell are expected to step in to fill the void left by Engram. The Jaguars will also be missing several other players, including defensive back Darnell Savage and multiple offensive and defensive linemen. An update on Engram's injury status is anticipated after the game.