Missouri quarterback Brady Cook is doubtful for the upcoming game against Alabama due to a high ankle sprain sustained during a comeback win over Auburn. Despite leading the Tigers to victory after undergoing an MRI, Cook has been extremely limited in practice, leaving his status uncertain. Missouri will also likely miss running back Nate Noel, who is dealing with a foot injury, potentially leaving Marcus Carroll to take over as the primary tailback. Missouri's defense, ranked seventh nationally, could pose a challenge to an Alabama offense that has struggled recently. The Tigers face significant challenges with key players potentially sidelined, testing their depth and resilience against a strong Alabama team. Coach Eli Drinkwitz has not confirmed Cook's participation in practice, adding to the uncertainty surrounding his availability for the game.