The Buffalo Bills secured a 34-28 victory over the Arizona Cardinals in their season opener, led by standout performances from quarterback Josh Allen and defensive end Greg Rousseau. Allen threw for two touchdowns and ran for two more, including a spectacular 6-yard leap over Budda Baker, despite injuring his left hand. Rousseau recorded three sacks, contributing significantly to the defense. The Bills overcame a 17-3 deficit in the first half, showcasing resilience and effective halftime adjustments. Taron Johnson's early injury was a concern, but the team managed to compensate defensively with key plays from Ja’Marcus Ingram and others. The victory highlighted both the team's high-powered offense and areas needing improvement as they move forward in the season.