Virginia at Louisville Headlines Week 6

Week 6 college football attention centers on No. 24 Virginia visiting undefeated Louisville in an ACC showdown that drew ESPN College GameDay; Trell Harris is a key vertical threat as Virginia seeks its first road win. Louisville, about a 7.5-point favorite, is relying on an improved, physical defense to slow Chandler Morris and UVA's attack. BYU improved to 5-0 after beating West Virginia and could enter the AP Poll depending on Saturday results, notably the Virginia–Louisville and Michigan matchups. Utah, coming off a 48–14 road win over West Virginia, goes into a bye at 4-1 but has seen its College Football Playoff and Big 12 title odds slip after a lopsided loss to Texas Tech. Oregon gets a timely bye before a top-10 game with Indiana, while Oregon State travels to Appalachian State still searching for its first win and with game viewing and radio details announced. Miscellaneous notes: Arizona State is using the bye to refine its offense, Arkansas concluded fall scrimmages, and 49ers quarterback Mac Jones briefly left with a knee issue but returned.