The San Francisco 49ers are managing multiple roster changes and contract disputes ahead of the 2024 NFL season. Wide receiver Brandon Aiyuk's status remains uncertain amidst unresolved contract negotiations, despite the 49ers' preference to keep him. The team placed running back Elijah Mitchell on injured reserve, ending his season, and activated safety Talanoa Hufanga from the PUP list. To add depth, the 49ers signed wide receiver Terrace Marshall Jr. and veteran safety Tracy Walker. Significant roster cuts include the release of recent draft picks tight ends Cameron Latu and Brayden Willis. Additionally, the 49ers are considering a trade for Buccaneers' edge rusher Joe Tryon-Shoyinka to bolster their defensive depth.