Texans GM Confirms RB Joe Mixon to Miss First Four Games with Ankle Injury

Houston Texans running back Joe Mixon has been placed on the Reserve/Non-Football Injury list due to an ankle injury sustained in the offseason, making him ineligible to play in at least the first four games of the 2025 season. Texans GM Nick Caserio expressed uncertainty about Mixon's return, stating that the team will evaluate his progress after the four-week period and that no clear timeline exists for his comeback. Mixon's absence leaves a significant gap in the Texans' backfield, as he was a key contributor last season with over 1,000 rushing yards and Pro Bowl honors. To compensate, the Texans will rely on veteran Nick Chubb, who is currently in concussion protocol, Dameon Pierce, and rookie Woody Marks to carry the running game. Caserio emphasized confidence in the existing roster's ability to contribute, although the situation remains precarious given Mixon's uncertain status and Chubb's injury concerns. Fans and analysts will be closely watching how the Texans manage their offense early in the season without a fully available Mixon.