The Six Nations opener between Ireland and France will take place at Stade Vélodrome in Marseille, due to renovations at the original venue, Stade de France. Ireland, missing key players including the retired Johnny Sexton, is set to defend their Grand Slam title. This marks their first competitive match since their Rugby World Cup quarter-final defeat. Despite the absence of former leadership and the challenges, the team, led by captain Peter O'Mahony, is focused on maintaining their success.