General Hospital Characters Face Shocking Revelations Amid Monica's Passing

General Hospital spoilers for the week of September 22-26, 2025, reveal major developments including the upcoming death and memorial of Monica Quartermaine, which deeply affects the Port Charles community. Sonny and Carly learn of Monica's passing and grapple with their grief while Martin makes a mysterious phone call related to Monica. Anna Devane receives shocking intel concerning two key cases—the Judge Heran death and Drew's shooting—which could shift suspicions and affect multiple characters. Meanwhile, Britt Westbourne is shaken as she struggles with her new life and job, and her past in Croatia may be connected to recent events. Nina Reeves' secret about secretly paying Ric Lansing to represent Willow Tait is at risk of being exposed by Ava Jerome, who aims to eliminate competition for Ric. Additionally, there are hints of changes within the Quartermaine family, including a possible rule change about keeping dogs in the stables, and emotional moments as characters face personal challenges and losses.