49ers Start 2025 Season 2-0 With Defense-Led Road Wins

The San Francisco 49ers have started the 2025 NFL season with a strong 2-0 record, including a 26-21 road win over the New Orleans Saints despite missing key starters like quarterback Brock Purdy and tight end George Kittle. The team's defense, heavily revamped in the 2025 draft with six of eleven picks focused on defense, is already showing promise, highlighted by rookie Mykel Williams who has made impactful plays alongside Nick Bosa. Backup quarterback Mac Jones, who started in place of Purdy, delivered a solid performance with 279 yards and three touchdowns, demonstrating he can run Kyle Shanahan's offense effectively and providing a dependable alternative at quarterback. The 49ers also benefited from offseason acquisitions such as pass rusher Bryce Huff, who made a crucial strip sack to seal the win, and receiver Jauan Jennings, who emerged as a key offensive contributor with a 42-yard touchdown catch. Historically, starting the season 2-0 with back-to-back road wins is a positive indicator for the 49ers, as they have often reached the Super Bowl under similar circumstances. Overall, the combination of a retooled defense, effective quarterback play, and strategic offseason additions bodes well for San Francisco's 2025 campaign.