49ers Brace for Weeks Without Key Linemen Huff, Brendel Amid Hamstring Injuries

The San Francisco 49ers will be without two key starters, center Jake Brendel and edge rusher Bryce Huff, due to hamstring injuries expected to sideline them for at least two weeks. Huff, who has been the team's leading pass-rushing threat following Nick Bosa's season-ending torn ACL, suffered the injury near the end of their recent win over the Atlanta Falcons. This compounds the 49ers' defensive end depth issues, with Yetur Gross-Matos also sidelined by a hamstring injury, leaving only a few healthy players at the position. Despite these setbacks, coach Kyle Shanahan remains hopeful Huff will return soon and does not believe the injuries increase urgency in seeking trade market help before the November deadline. Brendel's injury occurred during the second quarter of the same game, and Matt Hennessy has stepped in as his replacement. The 49ers face challenges managing their roster depth as they prepare for upcoming road games against Houston and the New York Giants.