Minnesota Vikings star wide receiver Justin Jefferson suffered a leg injury during the second half of their Week 2 game against the San Francisco 49ers. Jefferson was injured while blocking for a running play, colliding with 49ers defensive end Nick Bosa, who also sustained an ankle injury but was able to return. Before leaving the game, Jefferson had an impressive performance with four receptions for 133 yards, including a 97-yard touchdown. The Vikings announced he was questionable to return after being evaluated in the medical tent. With Jefferson's absence, Minnesota was left to rely on reserves, as starter Jordan Addison was already out due to an ankle injury. Jefferson's health is critical for the Vikings, as he is a key component of their offense.