Orlando Brown Ruled Out for Chargers Game

Cincinnati Bengals offensive tackle Orlando Brown has been ruled inactive for the Sunday night game against the Chargers due to a knee/fibula injury, despite practicing limitedly earlier in the week. He will aim to return for the Week 13 matchup against the Steelers after the Bengals' bye week. Meanwhile, Louisville's freshman running back Isaac Brown suffered a shoulder contusion during the first quarter of the game against Stanford, leading to his early exit. Before his injury, he had only gained three yards on two carries, and the Cardinals were trailing 3-0. Following Brown's departure, Louisville shifted to a running back by committee strategy, with Duke Watson scoring two touchdowns to help the team lead 21-13 by halftime. Isaac Brown had entered the game as one of the top performers in the FBS, averaging 7.55 yards per carry this season.