The sixth and final season of FX's acclaimed comedy series 'What We Do in the Shadows' is set to premiere on October 21 at 10 p.m. ET/PT, with the first three episodes available on FX and streaming on Hulu the next day. This season sees Guillermo reevaluating his life after a brief stint as a vampire, while the other vampires reflect on their lack of accomplishments over the past 50 years. The story will include the vampires entering the workforce and navigating human experiences, while also facing challenges in their relationships. The series has been nominated for eight Emmy Awards, demonstrating its critical success, and is based on the 2014 film by Jemaine Clement and Taika Waititi. Showrunner Paul Simms emphasizes that the final season will focus on humor rather than sentimentality. A panel discussion featuring the cast will take place at San Diego Comic-Con ahead of the premiere.