49ers McCaffrey Questionable Calf Injury Feels Great Ahead Seattle Opener

San Francisco 49ers running back Christian McCaffrey is set to play in the season opener against the Seattle Seahawks despite a calf injury that caused him to miss Friday's practice and be listed as questionable on the injury report. McCaffrey, who was limited in practice on Thursday, emphasized that he feels great and downplayed concerns stemming from his injury history, stating that sometimes things get blown out of proportion when he doesn't practice. He acknowledged that sitting out part of practice was a smart decision to avoid aggravating the issue, reflecting lessons learned from previous injuries. Last season, McCaffrey's calf issues, including bilateral Achilles tendinitis, limited him to just four games, but he expressed a focus on the present and readiness to perform. Head coach Kyle Shanahan confirmed McCaffrey did not practice on Friday but did not provide additional details about the injury. The 49ers also have other running backs available, including Brian Robinson, Isaac Guerendo, and rookie Jordan James, providing additional depth behind McCaffrey.