San Francisco 49ers wide receiver Deebo Samuel will miss a couple of weeks due to a calf strain sustained during the team's 23-17 loss to the Minnesota Vikings. Samuel, who led the team with 110 receiving yards in that game, joins star running back Christian McCaffrey on the sidelines, as McCaffrey is out for at least three games due to injuries. Coach Kyle Shanahan acknowledged the challenges posed by the injuries, emphasizing the need for the team to adapt. The 49ers currently have an open roster spot after placing McCaffrey on injured reserve, but it's unclear whether they will add depth at receiver or running back. Meanwhile, quarterback Brock Purdy is expected to rely more on Brandon Aiyuk and other role players as the team navigates these setbacks. Shanahan continues to express optimism about managing the roster's challenges moving forward.