Christian McCaffrey May Miss Remainder of Season

San Francisco 49ers running back Christian McCaffrey may face a season-ending injury after suffering a PCL injury during the team's 35-10 loss to the Buffalo Bills. Coach Kyle Shanahan confirmed that McCaffrey experienced a non-contact injury on a snowy field early in the game, leading to him being assessed in the medical tent before heading to the locker room on crutches. This incident marks another setback for McCaffrey, who had already missed eight games earlier this season due to Achilles tendinitis. If he cannot return, his season statistics will stand at 50 carries for 202 yards and 15 catches for 146 yards without any touchdowns. The 49ers may rely on Jordan Mason and Isaac Guerendo to fill the void in the backfield as they attempt to salvage their playoff hopes. McCaffrey's absence is part of a broader injury crisis for San Francisco, which has also seen key players like quarterback Brock Purdy sidelined recently.