Jesse Plemons has revealed he lost over 50 pounds through intermittent fasting, dismissing rumors of using the diabetes drug Ozempic. The actor shared that his weight loss journey took about a year and a half, motivated by the desire to keep up with his young children and improve his overall health. Plemons noted the significant increase in his energy levels and the positive impact on his mental health. Despite the prevalence of Ozempic in Hollywood, Plemons emphasized his natural approach to weight loss, which he found surprisingly effective. He initially decided to lose weight for a role in the film 'Civil War,' where he appeared alongside his wife, Kirsten Dunst.