Buffalo Bills Receiver Keon Coleman Out vs. Colts

The Buffalo Bills will face the Indianapolis Colts in Week 10 without key wide receiver Keon Coleman, who has been ruled out due to a wrist injury. Amari Cooper will also miss the game, forcing the Bills to rely heavily on Khalil Shakir and other wideouts like Mack Hollins and Curtis Samuel. The Colts, struggling offensively, will start Joe Flacco as they attempt to rebound from back-to-back losses, with the team looking to improve their performance on third downs. Despite having a relatively clean injury report, the Colts will be without star receiver Michael Pittman Jr., which adds to their offensive challenges. Both teams are facing significant obstacles, with the Bills needing to overcome their injury woes and the Colts aiming to revitalize their lackluster offense against a strong opponent. The matchup is critical for both teams as they navigate their respective challenges.