The Democratic Republic of Congo is experiencing the largest mpox outbreak on record, with a significant impact on children under 15 who account for the majority of deaths. Despite rich countries having millions of vaccine doses, only a small fraction has been pledged to Africa, far short of the 18-22 million doses needed. The WHO has prequalified Bavarian Nordic's IMVANEX as the first mpox vaccine, which could accelerate access in Africa. Countries like the US, EU, and Canada have begun donating vaccines, but logistical challenges delay their distribution. The Africa CDC and WHO are calling for increased donations and funding to address the outbreak, emphasizing that vaccines alone are not enough without awareness and testing.