Andre Pallante led the St. Louis Cardinals to a 4-0 victory over the Pittsburgh Pirates, striking out a career-high nine batters and allowing just four hits in seven innings. Paul Skenes, despite his strong performance with a 2.07 ERA and seven strikeouts over six innings, suffered the loss as the Pirates' bats were silent. The Cardinals' bullpen maintained the shutout with perfect innings from Andrew Kittredge and Ryan Fernandez. Key offensive contributions for the Cardinals included RBI singles from Nolan Arenado and Pedro Pagés, and an RBI double by Brendan Donovan. The Pirates' rookie Nick Yorke made his MLB debut and went 0 for 3 with a stolen base. This game marked the beginning of a four-game series between the teams.