Multiple highways across North America experienced significant closures due to serious traffic accidents. In Denver, a deadly crash involving two vehicles on southbound Interstate 25 led to the closure of lanes near 20th Street, with one person dead and another hospitalized. Oregon's Highway 18 east of McMinnville was shut down due to an accident, causing detours and delays. Ontario saw a multi-vehicle collision on Highway 401 near Comber, closing westbound lanes between Essex County Road 42 and Queen's Line. Additionally, in Anchorage, a serious injury accident on the Seward Highway near Portage resulted in the closure of both directions with no timeline for reopening. Authorities are investigating and providing detour routes in each of these incidents.