Ozempic, a weight-loss drug initially approved for treating Type 2 diabetes, has gained popularity for its significant weight-loss effects but comes with notable side effects and risks. While effective in suppressing appetite and reducing body weight by about 15%, concerns have been raised about the loss of lean mass, including muscle, which constitutes about 40% of the weight loss. Dr. Gabrielle Lyon and Dr. Peter Attia emphasize the importance of muscle mass in weight management, warning against the exclusive reliance on such drugs. Celebrities like Macy Gray have shared their adverse experiences, including severe constipation and hospital visits due to shortness of breath. The drug's sister medication, Wegovy, is set to become available in Australia, promising similar benefits but necessitating proper diet and exercise. Additionally, the phenomenon of 'Ozempic face,' characterized by sagging facial skin, has been observed among users who lose weight rapidly.