The Tennessee Titans (2-6) will face off against the Los Angeles Chargers (5-3) at SoFi Stadium on November 10, marking the 50th meeting between the two franchises. The Chargers, boasting the league's best defense, have won two consecutive games and allow just 12.6 points per game, while the Titans lead in total defense. Both teams have shown strong defensive performances recently, with the Titans forcing three turnovers in their overtime win against New England. Chargers quarterback Justin Herbert has been effective, not throwing an interception in his last six games, yet faces pressure from a Titans defense that has recorded eight sacks in two games. The matchup will be regionally televised on FOX, with kickoff set for 1:05 PM PT. Historically, the Chargers lead the series, but the teams have exchanged victories in recent matchups.