Studies suggest that inheriting the risk of Alzheimer's disease from one's mother may increase the likelihood of developing the condition, with higher amyloid levels observed in those with maternal family history. Research indicates that individuals with a history of preeclampsia during pregnancy are at a heightened risk for young-onset dementia. Understanding the impact of parental inheritance on dementia risk can aid in identifying those predisposed to the disease, with amyloid levels linked to family history and onset age of symptoms. The study underscores the importance of considering sex-specific parental history in assessing dementia risk and highlights the association between maternal inheritance and biological brain changes related to Alzheimer's disease.