George Kittle Inactive for Seahawks Game

San Francisco 49ers tight end George Kittle is inactive for their game against the Seattle Seahawks due to a hamstring injury, marking his second absence this season for the same issue. Despite hopes he could play, limited practice participation during the week and cautious pregame assessments led to him being ruled out. Kittle's absence is significant as he leads the team with 43 receptions for 560 yards and seven touchdowns, underscoring his role in the 49ers' red-zone offense. In contrast, Nick Bosa and Trent Williams, both previously listed as questionable, will play, with Bosa overcoming a painful hip injury and Williams dealing with an ankle issue. The 49ers have historically struggled without Kittle, losing 10 of the last 13 games he missed since November 2020. Despite Kittle's absence, the team remains optimistic about his return for the next game against the Green Bay Packers.