San Francisco 49ers star wide receiver Brandon Aiyuk's contract dispute remains unresolved, causing significant disruptions. Despite being cleared to practice by team doctors, Aiyuk has skipped multiple practices, risking substantial fines under the NFL's collective bargaining agreement. The 49ers had initially explored trading Aiyuk but found no suitable replacements, leading to his contract extension at $30 million per year, a costlier deal due to market misjudgments. The team has signed Terrace Marshall Jr. to bolster their receiver depth amid Aiyuk's holdout. With the regular season approaching, the 49ers are under pressure to resolve this stalemate or face opening without one of their key players.