Eric Dane Portrays ALS Patient in NBC Drama Following Diagnosis

Eric Dane, renowned for his roles in "Grey's Anatomy" and "Euphoria," publicly disclosed his diagnosis with amyotrophic lateral sclerosis (ALS) in April 2025. He is set to guest-star in season two, episode nine of NBC's medical drama "Brilliant Minds," portraying Matthew, a firefighter grappling with an ALS diagnosis, a role closely mirroring Dane's own health journey. ALS is a progressive and incurable nervous system disease that leads to loss of muscle control and paralysis, significantly impacting Dane's mobility, including the loss of function in his right arm and gradual decline in his left. Beyond acting, Dane is actively involved in ALS advocacy, working with the nonprofit "I Am ALS" and campaigning for federal funding to support research and care for those affected by the disease. Despite the sobering prognosis, Dane remains committed to his craft and uses his platform to raise awareness and support for the ALS community. "Brilliant Minds" focuses on neurological medical mysteries and will air the episode featuring Dane on November 24, 2025.