The mpox outbreak in Africa remains alarming, with cases rising by 177% and deaths increasing by 38.5% compared to last year, according to the Africa CDC. The World Health Organization (WHO) has declared the situation a global health emergency, prompting Gavi to purchase 500,000 doses of the mpox vaccine to assist with the crisis. While countries like Rwanda and the Democratic Republic of Congo are beginning vaccination campaigns, the Democratic Republic of Congo has reported over 4,900 cases and 629 deaths, highlighting the urgent need for more vaccines. In contrast, Kazakhstan reports a stable situation with no mpox cases and no requirement for vaccines. This disparity in the outbreak's impact underscores the challenges faced by African nations with weak health systems post-COVID-19. Despite some vaccines being delivered, significant gaps remain in addressing the outbreak adequately.