49ers Overcome Injury Plague to Defeat Falcons Led by McCaffrey

The San Francisco 49ers have demonstrated resilience during their 2025 NFL season despite being severely impacted by injuries to key players such as quarterback Brock Purdy, tight end George Kittle, defensive end Nick Bosa, and linebacker Fred Warner. Christian McCaffrey led the team to a 20-10 victory over the Atlanta Falcons with 201 yards from scrimmage and two touchdowns, supported by strong defensive performances from backups and younger players stepping up in the absence of starters. George Kittle made a significant impact upon his return from a hamstring injury, notably improving the 49ers' rushing game, which had struggled earlier in the season, with 151 of the team's 174 rushing yards coming when he was on the field. The team's ability to overcome injuries has been attributed to strong leadership and coaching, fostering resilience among the players and allowing the 49ers to remain competitive and in a good position for a playoff run. Despite the challenges, the team is optimistic about getting key players back to full strength and improving their overall performance as the season progresses. This ongoing pattern of injuries, however, continues to be a significant hurdle for the franchise, which has been among the NFL's most injured teams over recent years.