Study links high nifedipine doses to cardiac arrest risk

Recent developments in hypertension treatment include promising new drugs and important safety concerns. An experimental medication, lorundrostat, has been shown in a clinical trial to significantly reduce blood pressure in patients with uncontrolled hypertension who are already on multiple medications. At the same time, a mass recall of the hypertension drug Lisinopril is underway in France due to packaging errors that could lead to accidental overdose, though the medication itself remains safe. Additionally, a European study has identified a link between high doses of the blood pressure drug nifedipine and an increased risk of sudden cardiac arrest, while another commonly used drug in the same class, amlodipine, did not show this risk. These findings highlight both advances and ongoing risks in managing high blood pressure, emphasizing the need for careful medication management and awareness of new treatment options.