The Miami Dolphins are preparing to face the Buffalo Bills with a depleted lineup due to several key injuries. Defensive tackle Zach Sieler, who sustained a fractured orbital bone, and safety Jevon Holland, dealing with a knee injury, are both expected to miss the game, impacting Miami's defensive capabilities. Additionally, cornerbacks Kader Kohou and Storm Duck are unlikely to play, further straining the Dolphins' secondary. Despite these challenges, the Dolphins elevated Neil Farrell Jr. and Matt Overton from the practice squad, while wide receiver River Cracraft remains on injured reserve. Meanwhile, the Buffalo Bills, led by quarterback Josh Allen, are looking to consolidate their lead in the AFC East and maintain their strong start to the season. Allen's recent performance has been noteworthy, and the Bills are 9-1 in games where they score on their first offensive possession since 2023.