Ravens Lose 41-40 to Bills After Henry Fumble Decides AFC Opener

In the 2025 NFL season opener, the Baltimore Ravens lost a 41-40 game to the Buffalo Bills after surrendering a late lead, largely due to a critical fumble by running back Derrick Henry. Despite rushing for 146 to 169 yards and scoring two touchdowns, Henry took full responsibility for the turnover that allowed the Bills to mount a comeback and eventually win with a game-winning field goal by Matt Prater. Ravens teammates and analysts noted that while Henry's fumble was costly, the defense's inability to stop the Bills' 22-point fourth quarter and a missed extra point also contributed to the defeat. Ravens head coach John Harbaugh has faced scrutiny for the team's recurring pattern of losing big leads. Henry, who set several milestones during the game including surpassing Jim Brown in rushing touchdowns, expressed regret and emphasized the importance of ball security moving forward. The Ravens now look to recover mentally as they prepare to face the Cleveland Browns in Week 2.