Cameron Mathison and his wife Vanessa Mathison have announced their separation after 22 years of marriage, expressing a commitment to remain friends and prioritize their two children, Lucas and Leila. The couple shared a heartfelt statement emphasizing their gratitude for their years together and their mutual respect during this transition. They met in 1998 while modeling in New York City and married in July 2002. Cameron, known for his role on 'General Hospital,' has been open about his health struggles, including a kidney cancer diagnosis in 2019. Recently, he shared moments from his summer with their children on social media, which notably excluded Vanessa. The split coincides with the impending five-year anniversary of Cameron's cancer diagnosis, marking a significant period in their lives.