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Five-Minute Daily Exercise Lowers Blood Pressure, Study Finds
Recent research highlights multiple approaches to managing hypertension and its complications. A study led by the ProPASS Consortium found that even five minutes of daily physical activity, such as uphill walking or stair-climbing, can significantly lower blood pressure, emphasizing the importance of replacing sedentary behavior with exercise. Isometric exercise training (IET) has been shown through a series of studies to be an effective intervention for hypertension, influencing recent European hypertension guidelines. Additionally, Mineralys Therapeutics reported positive phase 2 trial results for lorundrostat, an aldosterone synthase inhibitor, which significantly reduced systolic blood pressure and albuminuria in patients with hypertension and chronic kidney disease. Another concern is exercise-induced hypertension (EIH) especially prevalent among long-distance runners, which increases the risk of cardiovascular events; blood flow restriction training is emerging as a promising method to lower resting blood pressure in hypertensive patients. These findings collectively reinforce exercise and novel therapies as crucial components in managing high blood pressure and reducing related health risks.

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