Chiefs Injury Questions Ahead of Monday Night Clash

Monday Night Football in Week 5 matches the 2-2 Kansas City Chiefs against the 3-1 Jacksonville Jaguars in a nationally televised primetime game. Jacksonville enters with an elite, takeaway-driven defense and a conservative but effective offense under head coach Liam Coen, and will wear their Prowler throwback uniforms. Kansas City, led by coach Andy Reid with Steve Spagnuolo scheming the defense and playmakers such as Chris Jones, is a narrow three-point favorite. The Chiefs are managing key injury questions — cornerback Kristian Fulton (ankle), defensive end Mike Danna (quadriceps) and defensive tackle Omarr Norman-Lott (shoulder) — which could blunt their pass rush and secondary depth. Jaguars coordinator Anthony Campanile emphasized that Patrick Mahomes remains uniquely difficult to prepare for, underscoring the challenge Jacksonville faces. Oddsmakers and analysts view the matchup as a potential upset opportunity if the Jaguars' defense can disrupt Kansas City's offense.